https://www.selleckchem.com/pr....oducts/SB-216763.htm
BACKGROUND Embryo implantation relies on precise hormonal regulation, associated gene expression changes, and appropriate female reproductive tract tissue architecture. Female mice exposed neonatally to the phytoestrogen genistein (GEN) at doses similar to those in infants consuming soy-based infant formulas are infertile due in part to uterine implantation defects. OBJECTIVES Our goal was to determine the mechanisms by which neonatal GEN exposure causes implantation defects. METHODS Female mice were exposed to GEN on postnatal days (