https://www.selleckchem.com/pr....oducts/tetramisole-h
Chinese hamster ovary (CHO) cells are currently the primary host cell lines used in biotherapeutic manufacturing of monoclonal antibodies (mAbs) and other biopharmaceuticals. Cellular energy metabolism and endoplasmic reticulum (ER) stress are known to greatly impact cell growth, viability, and specific productivity of a biotherapeutic. However, specific molecular mechanisms responsible for these changes are not fully understood. In a previous paper, we employed multi-omics profiling to investigate the impact of a reduction in c
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