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Emission rates and degradation rate constants were the most influential input parameters in SimpleBox based on sensitivity analysis. Suggestions for improvements of SimpleBox refining POP risk assessment are provided. V.Cadmium (Cd) contamination from mining and smelting operations has led to growing environmental health concerns. In this study, soil, surface water, drinking water, rice, vegetables, and biomarkers (hair and urine) were collected from local residents near an active lead-zinc mine and a copper smelter. The aim was to det