https://www.selleckchem.com/pr....oducts/Cladribine.ht
Compared with placebo, probiotics (RR=0.71; 95% CI 0.52 to 0.99), synbiotics (RR=0.45; 95% CI 0.28 to 0.73) and polyphenols (RR=0.30; 95% CI 0.13 to 0.7 were significantly associated with a lower risk of diarrhoea. Biotic supplements also reduced the risk of moderate to severe diarrhoea (RR=0.49; 95% CI 0.36 to 0.67) and the need for anti-diarrhoeal medication (RR=0.64; 95%CI 0.44 to 0.92). In contrast, glutamine had no effect on acute symptoms (RR=1.05; 95% CI 0.86 to 1.29). There was a non-significant trend for reduction in nause