https://www.selleckchem.com/pr....oducts/a-1155463.htm
simvastatin augmented B cells, CD4 lymphocytes, CD8 lymphocytes, and tumor-specific CD8 in the tumor-draining lymph nodes. However, only the treatment combination increased the numbers of these lymphocyte populations in the tumor microenvironment and in the spleen. In conclusion, blockade of IFNα functions by simvastatin markedly enhances lymphocyte infiltration and the antitumor activity of MVA, prompting a feasible drug repurposing. In conclusion, blockade of IFNα functions by simvastatin markedly enhances lymphocyte infiltration an
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