https://www.selleckchem.com/pr....oducts/nedisertib.ht
Many studies have recorded significant impairment of health-related quality of life in systemic sclerosis patients using validated scales. However, these instruments are not specifically designed for facial signs. To develop and validate a specific questionnaire to assess the burden on patients with facial signs of systemic sclerosis and which we have named "Burden of Face Affected" (BoFA). BoFA was developed using standard methodology in 3phases exploration, development and validation. In all, 197patients completed questionnaires. W