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Median value of CD8 positive percentage in RGP was lower than that in non-RGP (0.75 vs 1.46, P = .04). Median overall survival times in low CD8 groups tend to be shorter than those in high CD8 group (8.2 vs 4.2 months). CONCLUSION Most LMs from PCa show a homogeneous GP. The RGP was observed in about a half of the LMs from PCa patients, and was identified as a poor prognostic factor. © 2020 The Authors. Cancer Medicine published by John Wiley Sons Ltd.Polyploid giant cancer cells (PGCC) represent a poorly understood, small subpopu
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