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Best Medication For ADHD The use of medication is an integral part of most treatment plans for ADHD. Finding the right dosage and medication can take some time. Be patient and communicate openly with your GP or specialist. Stimulants increase the levels of the chemicals that regulate behavior in the brain. They are available in short-acting formulas and long-acting ones. Short-acting medicines reach their peak within just a few hours and are typically taken 3-4 times per day. Long-acting medicines last between 8 and 12 hours and are typically