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In the IV + IA group, a decrease in blood loss was observed compared to the no TA group (+ 220ml 95% confidence interval [CI] [184; 255] of RBC 0.001) and in the IA group (+ 65ml 95% CI [30; 99] of RBC 0.001). The length of hospital stay of the IV + IA group was shorter compared to the no TA group (hazard ratio [HR] 0.35, 95% CI [0.29; 0.43], 0.001) to the IA group (HR 0.57, 95% CI [0.48; 0.69], 0.001) and the IV group (HR 0.45, 95% CI [0.39; 0.50], 0.001). One case of deep vein thrombosis occurred in the g