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For Adults The stimulants like methylphenidate amphetamine and various brain chemicals can aid in increasing levels. Nonstimulants, like atomoxetine and antidepressants, operate slower than stimulants, but they can be beneficial too. The comorbidity of conditions can affect the effectiveness of ADHD medication. The most serious symptom of any comorbidity should be treated first. Then, the doctor must be able to determine if ADHD symptoms improve. Medication Adults with ADHD are most often treated by medicat