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05). Fish in the control and CPF groups displayed downregulated CAT whereas the expression of GPX and CAT genes was higher in fish of the MOS/CPF group than fish in the MOS group (P less then 0.05). MOS upregulated the expression of HSP70 gene with CPF toxicity. Fish of the CPF and MOS/CPF groups displayed upregulated CASP3, IFN-γ, and IL-8 genes. Fish of the CPF group exhibited the lowest IL-1β, while fish of the MOS/CPF group showed upregulated IL-1β. The intoxication with CPF induced histopathological inflammations in the gills, intest