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Results One-hundred and forty-three surveys were completed resulting in a survey response rate of 90%. PAAST knowledge scores (mean±SD) increased overall following the FDIS on PAAST (6.67±1.51 vs. 7.81±1.39). Knowledge scores increased considerably for questions related to penicillin allergy consequences, cross-reactivity, and correct steps of PAAST. Pharmacy students' PAAST confidence scores (mean±SD) also improved following the interactive instruction and simulation (2.30±0.70 vs. 3.22±0.67) with considerable confidence increases in pe