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First Line Treatment For ADHD in Adults Certain people suffering from ADHD discover that medication can help to manage their symptoms. The stimulants, like amphetamine and methylphenidate are effective in boosting activity in brain areas that control attention and behaviour. Other medications, like the non-stimulant drug atomoxetine and antidepressants that work differently, but are still effective. Patients who are taking medication should visit their GP regularly to check for the body's reactions and ad