https://www.selleckchem.com/pr....oducts/estradiol-ben
We investigated whether particular immunoglobulin GM (γ marker) alleles-individually or epistatically with a known human leukocyte antigen (HLA) risk allele-were associated with the development of Alzheimer disease (AD). Using a prospective cohort study design, we genotyped DNA samples from 209 African American (AA) and 638 European American (EA) participants for IgG1 (GM 3 and GM 17), IgG2 (GM 23+ and GM 23-), and rs9271192 (A/C) alleles by TaqMan and rhAMP genotyping assays. In EA subjects, none of the GM or HLA alleles-ind