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These data support further medicinal chemistry lead-optimization of DDD01034957 as a novel antimalarial chemical class and provide new insights to further reduce in vivo metabolic clearance.Whole genome sequencing (WGS) has been shown to be superior to traditional procedures of genotyping in tuberculosis (T, nevertheless, reports of its use in drug resistant TB (DR-T isolates circulating in Mexico, are practically unknown. Considering the above the main of this work was to identify and characterize the lineages and genomic transmiss
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