https://www.selleckchem.com/pr....oducts/nec-1s-7-cl-o
001). Mediation analyses indicated increased GPR15 expression accounted for roughly half of the relationship between smoking variables and pro-inflammatory to anti-inflammatory cytokine balance. CRP was not associated with cannabis or tobacco use or GPR15+ expression, but was associated with body mass index (p0.001). These relationships persisted after controlling for lifestyle and medical factors impacting immune function. Increased expression of GPR15 by helper T cells in smokers may mediate some of the relationship bet