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Also, relative recoveries ranged from 115% to 111% for CO and MTA, respectively, demonstrating the applicability of the proposed method. Matrix effect, which has been statistically evaluated, is not significant, showing that the extraction selectivity can compensate the circumvent of the chromatographic separation.Intensive efforts have been made to diminish ethyl carbamate in fermentation products. The presented research demonstrated an approach to simultaneously detecting ethyl carbamate and its precursors including urea, citrulline a