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Effective postoperative analgesia leads to early mobilization, fewer pulmonary complications, and shorter hospital stay. We compared the analgesic effects of ultrasound-guided intercostal nerve (ICN) blocks, subcostal transversus abdominis plane (SCTAP) block, and a control group in open cholecystectomy. This was a prospective, randomized controlled, double-blind, multi-arm and parallel study. The study was conducted on patients of American Society of Anaesthesiology Physical Status Classes I and II, either sex, 18-60 years of age, and b