https://www.selleckchem.com/pr....oducts/merbarone.htm
Introduction Tuberous sclerosis complex (TSC) is a multisystem neurocutaneous disorder. Angiofibromas (AF), fibrous plaques, and hypopigmented macules are the major skin findings in TSC. Topical sirolimus reduces the volume and redness of AF and other skin findings. However, the efficacy of early intervention and long-term treatment remains to be clarified. We investigated the efficacy of sirolimus gel for AF in children with TSC. Methods We recruited nine children (five boys; four girls) with TSC and AF. We used 0.2% sirolimus gel ov
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