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A similar effect was observed within 30 minutes at 750 μg/mL for extract and within 90 minutes at 500 μg/ml for extract. The results of our study showed that the saponin extracts of our plants roots possess potent dose and time dependant spermicidal effect. These natural products could therefore represent a safer and better tolerated alternative to chemical spermicides. The results of our study showed that the saponin extracts of our plants roots possess potent in vitro dose and time dependant spermicidal effect. These natural products