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776 (95% CI 0.677 to 0.875; p = less then 0.0001) for galectin-3 and an AUC of 0.963 (95% CI 0.929 to 0.997; p = less then 0.0001) for GDF-15. CONCLUSION In DKD patients the galectin-3 and GDF-15 levels were inversely related to the eGFR which was further confirmed by the ROC curve demonstrating the potential of galectin-3 and GDF-15 as a biomarker. AIMS The aim of this paper is to observe the change of aqueous humor levels of placenta growth factor (PlGF) and vascular endothelial growth factor (VEGF) in proliferative diabetic ret