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ors (45%) are at standard risk for cardiac dysfunction. CONCLUSIONS The results of this study will show the prevalence of preclinical cardiac dysfunction in Swiss childhood cancer survivors, inform whether speckle tracking echocardiography is more sensitive to cardiac dysfunction than conventional echocardiography, and give a detailed picture of risk factors for cardiac dysfunction. The results will help improve primary treatment and follow-up care of children suffering from cancer. CLINICALTRIAL Prospectively registered in ClinicalTrial