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Ten physically energetic men received 50 mg/per day's hydrocortisone at 800 a.m. for 5 days. Cortisol, DHEA, and ACTH levels in plasma, and cortisol and DHEA levels in saliva had been determined the week before, right before (800 a.m.) and 2 h after (1000 a.m.) medication intake on days 1, 3, and 5 of treatment and day 1 post treatment. Hydrocortisone consumption induced an important escalation in both plasma cortisol (×3) and saliva cortisol (×1 levels 2 h after administrati