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Best Medication For ADHD The majority of ADHD treatment plans include medication. However, finding the right dosage and medication may take time. Be patient and communicate with your GP. Stimulants boost the levels of chemicals that control behavior in the brain. They are available in both short-acting and longer-acting versions. Short-acting drugs are at their peak in just a few hours and are taken 2-3 times per day. Long-acting medication lasts between 8 and 12 hours, and is usually taken only once a day. Stimulants Adults may not benefit f