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For sets correlating with M6-M6COS, some pairs had cytosines positioning to your reciprocal right (age.g., M3-M2COS and M6-M5COS), other pairs had cytosines positioning to your reciprocal left (e.g., M2-M3COS; M5-M6COS). Significant pair-to-pair correlations appeared between main-strand and COS CpG pairs. Through visual representations, we hypothesized that DNA folded to looping conformations the C1GG C2GG C3GG and C5G C6G themes would be near enough to allow cytosines 1-2-3 to interac