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In this review, we summarize the research on the most promising bacterial candidates with therapeutic properties with a specific focus on diabetes. To predict serum segesterone (SA) and ethinyl estradiol (EE) levels after 364 days of hypothetical continuous use (without removal) of a cyclic contraceptive vaginal system (CVS) containing 0.15 mg SA and 0.013 mg EE. We used pharmacokinetic (PK) data (n=37) from a multicenter, open-label, nonrandomized study of healthy women (18-38 years) that used the CVS for 13 cycles in a 21 days-in/7 da
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