https://www.selleckchem.com/pr....oducts/Tigecycline.h
Increased airway smooth muscle mass is a key pathology in asthma. Bronchial thermoplasty is a treatment for severe asthma based on selective heating of the airways that aims to reduce the mass of airway smooth muscle cells (ASMCs), and thereby bronchoconstriction. However, short heat exposure is insufficient to explain the long-lasting effect, and heat shock proteins (HSPs) have been suggested to play a role. We sought to determine the role of HSP70 and HSP90 in the control of airway wall remodeling by bronchial thermoplasty. Bronch