https://www.selleckchem.com/pr....oducts/cirtuvivint.h
Adjusted and unadjusted models had similar results. Longer illness duration, higher number of depressive episodes, longer duration of most severe manic/hypomanic episode, co-morbid anxiety disorders, and family history of suicide were associated with reduced HRV, as was bipolar depression severity in the participants experiencing a depressive episode. Finally, a higher IBI score was associated with lower HRV. High illness burden is associated with reduced HRV in BD. While the IBI needs to be validated in a larger sample, it may prov
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