https://www.selleckchem.com/pr....oducts/uamc-3203.htm
Brain-derived neurotrophic factor (BDNF) is a pro-survival factor in the brain that also regulates energy balance. loss-of-function point mutations are responsible for haploinsufficiency, causing severe early-onset obesity. Up to date, only a few studies have sequenced this gene to search for rare mutations related to obesity. In this study, we aimed to investigate the prevalence of variants in a cohort of adults with severe obesity from Brazil. This study comprised 201 adults with severe obesity (BMI ≥ 35.0 kg/m ) with onset during c
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