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Adult ADHD and Comorbid Disorders Many people with ADHD also suffer from comorbid conditions like major depression (Kessler and colleagues, 2006). Many patients do not respond to depression medications and may benefit from psychotherapy. Treatments that are most effective in reducing core symptoms of ADHD are those that boost and balance levels of specific neurotransmitters, which are brain chemicals. The most frequently prescribed stimulants include methylphenidate, amphetamine and other similar drug
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