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Hydroxocobalamin is a form of manufactured, injectable vitamin B12. Clinicians use it in the prevention and treatment of macrocytic anemia associated with vitamin B12 deficiency. It may also be part of therapy to treat Leber's optic atrophy (an inherited optic neuropathy associated with a deficiency in vitamin B12). It is also an antidote in cases of cyanide poisoning, including tobacco amblyopia (a visual disorder caused by tobacco that contained cyanide). Hydroxocobalamin is particularly useful in the treatment of vitamin B12 deficien