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Furthermore, ZnONPs can increase sub-G1 population as compared to negative control. Our findings showed that ZnONPs induce apoptotic activity and can modulate metastasis by up-regulating of and gene expression in two breast cancer (MCF-7 and T47D) cells. Our findings showed that ZnONPs induce apoptotic activity and can modulate metastasis by up-regulating of KAI-1 and NM23 gene expression in two breast cancer (MCF-7 and T47D) cells. The application of non-viral systems for delivering genes to cells is becoming a very interesting issue,
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