https://www.selleckchem.com/pr....oducts/poziotinib-hm
Furthermore, we found CIRBP mediated cardiac ubiquinone (CoQ10 ) biosynthesis play an important role in extending heart preservation and ubiquinone biosynthesis protein COQ9 was an essential down-stream regulator during this process. Finally, we found that zr17-2, a CIRBP agonist, could enhance the expression of CIRBP, which further enhances the synthesis of CoQ10 and promotes scavenge of reactive oxygen species and ATP production to extend the heart preservation. This study demonstrated that CIRBP enhanced CoQ10 biosynthes
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