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001) and perineural invasion (P = 0.04. Female, depth of tumor invasion (P = 0.001), and lymphatic invasion (P less then 0.001) were significant independent predictive factors for lymph node metastasis in multivariate analysis. Conclusion Positive LN status predicted poor disease-free survival in patients with early cancer. This suggests that depth of tumor invasion ≥ sm2 and the presence of lymphatic invasion in early colon cancer provide useful information to determine which patients would benefit from radical surgery.Background Road t