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But Gysi's scientific influence was by no means limited to prosthetics. Rather, he also provided important studies on caries and the dental pulp. Moreover, he published fundamental work on dental histopathology and microphotography. The current image of Gysi therefore needs to be revised. In view of the thematic breadth of his scientific contributions, Gysi is not only the most important prosthodontist of his time, but also one of the most versatile and innovative representatives in the history of Swiss dentistry. Sickle cell diseas