https://www.selleckchem.com/pr....oducts/Semagacestat(
Nelfinavir is a human immunodeficiency virus protease inhibitor that is currently being repositioned as an anticancer drug. Chloroquine, an anti-malarial lysosomotropic drug, inhibits autophagy. It has been reported that the combination of nelfinavir and chloroquine significantly enhances endoplasmic reticulum (ER) stress and induces selective cell death in multiple cell line models (in vitro). We assessed the effects of the combination of these drugs on human NSCLC cell lines in vitro using cell proliferation assay and p
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