https://www.selleckchem.com/products/colcemid.html
Major depressive disorder is a common illness that severely decreases psychosocial functioning. Due to the major limitations of current treatments including response failure, it is crucial to develop better therapy strategies. Evidence suggests that dopamine dysregulation might play a major role in major depressive disorder physiopathology. This study investigates whether the dopamine D1 receptor agonist A77636 modulates antidepressant-like activity in rats. Rats were injected with an acute single dose of A77636 (0.75, 1.5 or 3 mg/kg),
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