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15; 95% confidence interval 1.21-22.0, p=0.03). In contrast, patients with lower IBS and LDL-C 70mg/dL had an improved prognosis comparable with those with higher IBS. Addition of LDL-C levels to the baseline model of risk factors improved net reclassification improvement (NRI) and integrated discrimination improvement (IDI) in patients with lower IBS (NRI, 0.44, p=0.04; and IDI, 0.035, p0.01), but not in those with higher IBS. Evaluation of echolucency of the carotid artery was useful for selecting CAD patients at high risk of se