https://www.selleckchem.com/pr....oducts/abbv-2222.htm
Foetal brain and muscle are the tissues whose enhancers show the strongest depletion of archaic alleles, but only brain enhancers show evidence of unusually stringent purifying selection. We conclude that epistatic incompatibilities between human and archaic alleles are needed to explain the degree of archaic variant depletion from foetal muscle enhancers, perhaps due to divergent selection for higher muscle mass in archaic hominins compared with humans.Spinal cord injury (SCI) leads to wide-spread neurodegeneration across the neuroax
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