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ADHD in Adult Women Treatment ADHD symptoms can be aggravated by hormonal fluctuations. They may be more prominent during ovulation, or at other times during the menstrual cycle. They can also fluctuate from day to day depending on hormone levels. Women and girls often have less obvious signs than boys or men and are therefore less likely to be diagnosed. The disorder can have a serious impact on their lives. Medicines Women with ADHD often have a harder to be diagnosed and treate