https://www.selleckchem.com/pr....oducts/pf-477736.htm
Recent studies have demonstrated that inhibition of CD26 potentiates stromal cell-derived factor-1α (SDF-1α) promotes tissue regeneration and suppresses the rejection of organ transplants. This study investigated whether the combination of a CD26 inhibitor (CD26i) with granulocyte colony-stimulating factor (G-CSF) and short-term immunosuppressants modulates vascularized composite tissue allotransplant (VCA) survival in a rodent orthotopic hindlimb allotransplant model. The hindlimb allotransplantation from Brown-Norway to Lewis rats w