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The present study is an attempt to check the protective effect of fresh wheatgrass juice (WJ) as a potential therapeutic agent against alcohol-induced oxidative/nitrosative stress leading to nephrotoxicity in rats. Administration of 20% ethanol (5 g/kg b.wt/day) for 60 days resulted in a significant rise in the plasma concentrations of urea and creatinine with decreased levels of uric acid. Besides, a significant decrease in plasma electrolyte/mineral levels along with decreased activity of Na+/K+-ATPase activity was recorded in alcohol a
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