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Since 2007, french guidelines have recommended HPV vaccination for female aged to 14-23 yrs . old then 11 to 19 years of age in 2012, and extended to men who possess sex with men aged as much as 26 years in 2016. The influence of HPV vaccine programm regarding reduced amount of high grade cervical precancerous lesions in women ended up being restricted to a very reasonable vaccine coverage in Franc