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ADHD OTC Medication The majority of children and adults who are taking ADHD medication will experience side effects. They usually include loss of appetite as well as stomach upsets and changes in heart rate. These effects can be minimized through a balanced diet and enough sleep. The effects of stimulants boost the signaling between brain cell, which helps kids control their impulses and focus. However, they can cause tics and raise blood pressure. These drugs are controlled substances that can