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We show here that in the lack of sugar, the poly-histidine tract has an extra function, connecting collectively carbon and metal metabolism. Under problems of iron starvation, when various iron-intense mobile methods compete for this scarce resource, Snf1 is inhibited. The inhibition is via an interaction associated with the poly-histidine system with the low-iron transcription element Aft1. Aft1 inhibition of Snf1 occurs in the nucleus during the nuclear membrane, and just inhib