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The GO terms and paths had been appropriate with reproductive procedures, e.g., oxytocin signaling path, thyroid hormone synthesis and GnRH signaling pathway, vascular smooth muscle mass contraction and lipid metabolism (alpha-Linolenic acid metabolic rate and Linoleic acid kcalorie burning), etc. On the basis of the results, six possible candidate genes ESR1, OXTR, MAPK1, RYR1, PDIA4, and CYP19A1, under positive choice regarding faculties of multiparous sheep types were revealed. Our results enhance our