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, and reliable tool for general palliative care providers in Thailand to identify patients who might benefit from palliative care. Abnormal energy metabolism is one of the characteristics of tumor cells, and it is also a research hotspot in recent years. Due to the complexity of digestive system structure, the frequency of tumor is relatively high. We aim to clarify the prognostic significance of energy metabolism in digestive system tumors and the underlying mechanisms. Gene set variance analysis (GSVA) R package was used to establis