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Medline, Embase, Science Citation Index, Wanfang, CNKI, and Wiley on line Library had been thoroughly searched to identify appropriate scientific studies. Scientific studies had been assessed for methodological quality utilizing the Grading of tips Assessment, developing and Evaluation (LEVEL) system. Chances proportion (OR) and weighted mean difference (WMD) with 95% self-confidence period (CI) were used to assess the effectiveness of the association. Heterogeneity, subgroup, sensitiveness analyses, and