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INTRODUCTION Central neurological gait abnormalities (CNGA; i.e. frontal or parkinsonian) are frequently associated with neurodegenerative conditions in older adults, but their pathophysiological substrates remain poorly described. This cross-sectional study aims to assess the association between cerebrospinal fluid (CSF) Alzheimer's biomarkers and CNGA. METHODS CSF biomarkers (phosphor-tau, total tau and Aβ1-42) were measured in 52 patients with CNGA (77.33 ± 6.09 years; 28.8% female). Gait phenotypes were evaluated by two diagnosis-bl