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lained 38.8% (R 2 = 0.388) of the variance and the model was a significant predictor of PWV [F (6, 29) = 3.060, p = 0.019], however, none of the integrated covariates (BMI, number of shuttle run rounds, VO2max, dominant hand-grip strength) contributed significantly to the model. The lack of associations between fitness, strength and arterial stiffness might be explained by the few harmful lifestyle factors influencing vascular changes in the first decade of life.Toll-like receptors (TLRs) were first identified as molecular sensors that tra